WebDec 1, 2005 · In this issue of Clinical Cancer Research, Wolf and colleagues present compelling evidence that underscores a key role for regulatory T cell–induced immune suppression in tumor pathogenesis (1). Although most cancer patients mount innate and adaptive antitumor reactions, the evolution of clinically evident disease implies a failure … WebMar 15, 2014 · The innate cellular and molecular components required to mediate effective vaccination against weak tumor-associated antigens remain unclear. In this study, we used polymeric cancer vaccines incorporating different classes of adjuvants to induce tumor protection, to identify dendritic cell (DC) subsets and cytokines critical to this efficacy.
Current status and future directions of cancer immunotherapy
WebVanneman, M., & Dranoff, G. (2012). Combining immunotherapy and targeted therapies in cancer treatment. Nature Reviews Cancer, 12(4), 237–251. doi:10.1038/nrc3237 WebDec 2, 2011 · This review addresses the major challenges related to the translation of cancer nano-based vaccines to the clinic, discussing the requirements for ex vivo and in vivo models of cancer to ensure ... cycloheximide preparation
Immune Cell Types and Secreted Factors Contributing to Inflammation …
WebSource: Dranoff G. Nat Rev Cancer 2004;4:11-22. The immune system comprises two arms functioning cooperatively to provide a comprehensive protective response: the … WebDec 2, 2011 · The recent demonstration that cancer immunotherapy extends patient survival has reinvigorated interest in elucidating the role of immunity in tumour … cycloheximide mechanism